英语 英语 日语 日语 韩语 韩语 法语 法语 德语 德语 西班牙语 西班牙语 意大利语 意大利语 阿拉伯语 阿拉伯语 葡萄牙语 葡萄牙语 越南语 越南语 俄语 俄语 芬兰语 芬兰语 泰语 泰语 泰语 丹麦语 泰语 对外汉语

Gene Mutation Linked to Type 2 Diabetes

时间:2011-03-10 06:14来源:互联网 提供网友:xx6436   字体: [ ]
特别声明:本栏目内容均从网络收集或者网友提供,供仅参考试用,我们无法保证内容完整和正确。如果资料损害了您的权益,请与站长联系,我们将及时删除并致以歉意。
    (单词翻译:双击或拖选)

    Scientists have identified a unique genetic2 mutation3 in about 10 percent of people with type 2 diabetes4(糖尿病) studied in the United States and Europe. The discovery could help some people learn if they are at risk of developing diabetes so they can seek early treatment and possibly avoid getting the disease altogether.
    More than 200 million people worldwide suffer from type 2 diabetes, a potentially fatal disorder5. The World Health Organization expects diabetes-related deaths to double by 2030. Diabetes strikes people in rich and poor countries alike. World Health Organization statistics show that more than 80% of diabetes deaths occur in low- and middle-income countries. Age and obesity6 are two risk factors for type 2 diabetes. Another is family history.
    "Diabetes is a very important disease that is increasing in every country in the world," says Dr. Ira Goldfine, who has been studying the DNA7 of people with and without diabetes. "And we need to know what causes it.  And we have to get better treatments for it."With type 2 diabetes, the body cannot turn blood sugar into energy.  When sugar builds up in the blood, it can lead to serious complications(复杂) including death. That's why people afflicted8 with the disease need to monitor their blood sugar.
    "I have to test my blood virtually every day and make sure that my blood sugar is in a relatively9 normal range," says Dr. Arthur Lyons was diagnosed with type 2 diabetes three years ago.
    It was while studying DNA that Goldfine and his colleagues isolated10 the genetic mutation.
    "We found a protein that’s important, and we found that there are defects of this protein in diabetics," he says.
    The gene1 that makes this protein is called HMGA-1. The protein is important because it is an insulin receptor, which enables insulin to attach to liver cells and converts blood sugar to energy.
    "If you don’t have the HMGA-1 gene, then you don’t make the insulin receptor, and if you don’t make the insulin receptor, insulin doesn’t work very effectively," says Goldfine.
    Goldfine is one of the co-authors of the study that found the HMGA-1 mutation in some Italian diabetics. The researchers then repeated the finding in American and French patients.  All patients were Caucasian. They found that about 10 percent of type 2 diabetics in the United States and Europe, again all Caucasian, have defects in this gene”
    "We have a screening test now to identify these people and people who are related to them so we can start treatment and intervention11 early," says Goldfine.
    Early intervention for people with the HMGA-1 mutation including lifestyle changes: getting enough exercise, keeping weight in the normal range and monitoring blood sugar could prevent some people from developing type 2 diabetes. The researchers also say understanding the genetic component12 of this disease could help doctors provide better treatments to patients with type 2 diabetes, or even one day correct the genetic defect and prevent the disease that way.(本文由在线英语听力室整理编辑


点击收听单词发音收听单词发音  

1 gene WgKxx     
n.遗传因子,基因
参考例句:
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
2 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
3 mutation t1PyM     
n.变化,变异,转变
参考例句:
  • People who have this mutation need less sleep than others.有这种突变的人需要的睡眠比其他人少。
  • So far the discussion has centered entirely around mutation in the strict sense.到目前为止,严格来讲,讨论完全集中于围绕突变问题上。
4 diabetes uPnzu     
n.糖尿病
参考例句:
  • In case of diabetes, physicians advise against the use of sugar.对于糖尿病患者,医生告诫他们不要吃糖。
  • Diabetes is caused by a fault in the insulin production of the body.糖尿病是由体內胰岛素分泌失调引起的。
5 disorder Et1x4     
n.紊乱,混乱;骚动,骚乱;疾病,失调
参考例句:
  • When returning back,he discovered the room to be in disorder.回家后,他发现屋子里乱七八糟。
  • It contained a vast number of letters in great disorder.里面七零八落地装着许多信件。
6 obesity Dv1ya     
n.肥胖,肥大
参考例句:
  • One effect of overeating may be obesity.吃得过多能导致肥胖。
  • Sugar and fat can more easily lead to obesity than some other foods.糖和脂肪比其他食物更容易导致肥胖。
7 DNA 4u3z1l     
(缩)deoxyribonucleic acid 脱氧核糖核酸
参考例句:
  • DNA is stored in the nucleus of a cell.脱氧核糖核酸储存于细胞的细胞核里。
  • Gene mutations are alterations in the DNA code.基因突变是指DNA密码的改变。
8 afflicted aaf4adfe86f9ab55b4275dae2a2e305a     
使受痛苦,折磨( afflict的过去式和过去分词 )
参考例句:
  • About 40% of the country's population is afflicted with the disease. 全国40%左右的人口患有这种疾病。
  • A terrible restlessness that was like to hunger afflicted Martin Eden. 一阵可怕的、跟饥饿差不多的不安情绪折磨着马丁·伊登。
9 relatively bkqzS3     
adv.比较...地,相对地
参考例句:
  • The rabbit is a relatively recent introduction in Australia.兔子是相对较新引入澳大利亚的物种。
  • The operation was relatively painless.手术相对来说不痛。
10 isolated bqmzTd     
adj.与世隔绝的
参考例句:
  • His bad behaviour was just an isolated incident. 他的不良行为只是个别事件。
  • Patients with the disease should be isolated. 这种病的患者应予以隔离。
11 intervention e5sxZ     
n.介入,干涉,干预
参考例句:
  • The government's intervention in this dispute will not help.政府对这场争论的干预不会起作用。
  • Many people felt he would be hostile to the idea of foreign intervention.许多人觉得他会反对外来干预。
12 component epSzv     
n.组成部分,成分,元件;adj.组成的,合成的
参考例句:
  • Each component is carefully checked before assembly.每个零件在装配前都经过仔细检查。
  • Blade and handle are the component parts of a knife.刀身和刀柄是一把刀的组成部分。
本文本内容来源于互联网抓取和网友提交,仅供参考,部分栏目没有内容,如果您有更合适的内容,欢迎点击提交分享给大家。
------分隔线----------------------------
TAG标签:   mutation  diabete
顶一下
(0)
0%
踩一下
(0)
0%
最新评论 查看所有评论
发表评论 查看所有评论
请自觉遵守互联网相关的政策法规,严禁发布色情、暴力、反动的言论。
评价:
表情:
验证码:
听力搜索
推荐频道
论坛新贴