Researchers make sperm from stem cell in dish

 WASHINGTON, Aug. 4 (Xinhua) -- Researchers have found a way to turn mouse embryonic¹ stem cells into sperm² and this finding opens up new avenues for infertility³ research and treatment, according to astudy published Thursday in the online edition of journal Cell,

A Kyoto University team coaxed⁴ mouse embryonic stem cells into sperm precursors⁵, called primordial⁶ germ cells (PGCs), and shown that these cells can give rise to healthy sperm. The researchers say that such in vitro reconstitution of germ cell development represents one of the most fundamental challenges in biology.

When transplanted into mice that were unable to produce sperm normally, the stem cell derived⁷ PGCs produced normal-looking sperm, which were then used to successfully fertilize⁸ eggs. These fertilized⁹ eggs, when transplanted into a recipient¹⁰ mother, produced healthy offspring that grew into fertile male and female adult mice. The same procedure could produce fertile offspring from induced pluripotent stem cells that are often derived from adult skin cells.

"Continued investigations¹¹ aimed at in vitro reconstitution of germ cell development, including the induction¹² of female primordial germ cell-like cells and their descendants, will be crucial for a more comprehensive understanding of germ cell biology in general, as well as for the advancement¹³ of reproductive technology and medicine," the researchers wrote.

 

1 embryonic   

adj.胚胎的

参考例句：

• It is still in an embryonic stage.它还处于萌芽阶段。
• The plan,as yet,only exists in embryonic form.这个计划迄今为止还只是在酝酿之中。

2 sperm   

n.精子，精液

参考例句：

• Only one sperm fertilises an egg.只有一个精子使卵子受精。
• In human reproduction,one female egg is usually fertilized by one sperm.在人体生殖过程中，一个精子使一个卵子受精。

3 infertility   

n.不肥沃，不毛；不育

参考例句：

• It is the Geneva, Switzerland-based Biotech Company's second recombinant infertility drug. 它是瑞士生物技术公司在日内瓦的公司生产的第二种重组治疗不孕症的药。 来自英汉非文学 - 生命科学 - 生物技术制药疫苗
• Endometritis is a cause of infertility. 子宫内膜炎是不育的原子。 来自辞典例句

4 coaxed   

v.哄，用好话劝说( coax的过去式和过去分词 )；巧言骗取；哄劝，劝诱

参考例句：

• She coaxed the horse into coming a little closer. 她哄着那匹马让它再靠近了一点。
• I coaxed my sister into taking me to the theatre. 我用好话哄姐姐带我去看戏。 来自《现代汉英综合大词典》

5 precursors   

n.先驱( precursor的名词复数 )；先行者；先兆；初期形式

参考例句：

• Phenyl (or polyphenyl) substituted epoxides serve as excellent precursors to phenyl (or diphenyl) carbenes. 某些苯代（或多苯）环氧乙烷是制取带苯环（或二苯）碳烯的极好原料。 来自辞典例句
• Note the presence of megakaryocytes, erythroid islands, and granulocytic precursors. 可见巨核细胞，红细胞岛和粒细胞前体细胞。 来自互联网

6 primordial   

adj.原始的；最初的

参考例句：

• It is the primordial force that propels us forward.它是推动我们前进的原始动力。
• The Neanderthal Man is one of our primordial ancestors.的尼安德特人是我们的原始祖先之一.

7 derived   

vi.起源；由来；衍生；导出v.得到( derive的过去式和过去分词 )；（从…中）得到获得；源于；（从…中）提取

参考例句：

• Many English words are derived from Latin and Greek. 英语很多词源出于拉丁文和希腊文。 来自《简明英汉词典》
• He derived his enthusiasm for literature from his father. 他对文学的爱好是受他父亲的影响。 来自《简明英汉词典》

8 fertilize   

v.使受精，施肥于，使肥沃

参考例句：

• Fertilizer is a substance put on land to fertilize it.肥料是施在地里使之肥沃的物质。
• Reading will fertilize his vocabulary.阅读会丰富他的词汇。

9 Fertilized   

v.施肥( fertilize的过去式和过去分词 )

参考例句：

• The study of psychology has recently been widely cross-fertilized by new discoveries in genetics. 心理学研究最近从遗传学的新发现中受益匪浅。
• Flowers are often fertilized by bees as they gather nectar. 花常在蜜蜂采蜜时受粉。

10 recipient   

a.接受的,感受性强的 n.接受者,感受者,容器

参考例句：

• Please check that you have a valid email certificate for each recipient. 请检查是否对每个接收者都有有效的电子邮件证书。
• Colombia is the biggest U . S aid recipient in Latin America. 哥伦比亚是美国在拉丁美洲最大的援助对象。

11 investigations   

（正式的）调查( investigation的名词复数 )； 侦查； 科学研究； 学术研究

参考例句：

• His investigations were intensive and thorough but revealed nothing. 他进行了深入彻底的调查，但没有发现什么。
• He often sent them out to make investigations. 他常常派他们出去作调查。

12 induction   

n.感应，感应现象

参考例句：

• His induction as a teacher was a turning point in his life.他就任教师工作是他一生的转折点。
• The magnetic signals are sensed by induction coils.磁信号由感应线圈所检测。

13 advancement   

n.前进，促进，提升

参考例句：

• His new contribution to the advancement of physiology was well appreciated.他对生理学发展的新贡献获得高度赞赏。
• The aim of a university should be the advancement of learning.大学的目标应是促进学术。