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SSS 2009-03-19

时间:2010-05-17 06:38来源:互联网 提供网友:木渐浅。   字体: [ ]
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    (单词翻译:双击或拖选)

This is Scientific American's 60-Second Science. I'm Karen Hopkin. This will just take a minute.

Imagine antibiotics2 that would never lose their punch. New research focuses on drugs that bacteria simply can’t resist. Most antibiotics work by killing3 pathogens. The problem is, it’s hard to kill every single microbe. The rare ones that survive reproduce, often creating a population that’s antibiotic1 resistant4.

But what if you could make a drug that renders bugs5 harmless, without actually killing them? In that scenario6, bacteria might not evolve resistance. And that’s what researchers showed in the March 9th issue of Nature Chemical Biology.

The key is communication. In well-trained armies, commanders bark orders, and soldiers signal each other to coordinate7 their positions. The same is true for a lot of infectious bacteria, which hold off mounting a full assault—complete with toxins—until there are enough of them around.

The scientists designed three different compounds that jammed cell-to-cell signaling in bacteria that cause food poisoning and cholera8. And they found that the bugs remained sensitive to drugs, even after 26 generations. They still need to confirm that the bugs that are silenced are in fact less deadly. If so, the new antibiotics would leave bacteria alive, but they’d basically be POWs. With no way to escape.

 

Thanks for the minute for Scientific American's 60-Second Science. I'm Karen Hopkin.

 


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1 antibiotic KNJzd     
adj.抗菌的;n.抗生素
参考例句:
  • The doctor said that I should take some antibiotic.医生说我应该服些用抗生素。
  • Antibiotic can be used against infection.抗菌素可以用来防止感染。
2 antibiotics LzgzQT     
n.(用作复数)抗生素;(用作单数)抗生物质的研究;抗生素,抗菌素( antibiotic的名词复数 )
参考例句:
  • the discovery of antibiotics in the 20th century 20世纪抗生素的发现
  • The doctor gave me a prescription for antibiotics. 医生给我开了抗生素。
3 killing kpBziQ     
n.巨额利润;突然赚大钱,发大财
参考例句:
  • Investors are set to make a killing from the sell-off.投资者准备清仓以便大赚一笔。
  • Last week my brother made a killing on Wall Street.上个周我兄弟在华尔街赚了一大笔。
4 resistant 7Wvxh     
adj.(to)抵抗的,有抵抗力的
参考例句:
  • Many pests are resistant to the insecticide.许多害虫对这种杀虫剂有抵抗力。
  • They imposed their government by force on the resistant population.他们以武力把自己的统治强加在持反抗态度的人民头上。
5 bugs e3255bae220613022d67e26d2e4fa689     
adj.疯狂的,发疯的n.窃听器( bug的名词复数 );病菌;虫子;[计算机](制作软件程序所产生的意料不到的)错误
参考例句:
  • All programs have bugs and need endless refinement. 所有的程序都有漏洞,都需要不断改进。 来自《简明英汉词典》
  • The sacks of rice were swarming with bugs. 一袋袋的米里长满了虫子。 来自《简明英汉词典》
6 scenario lZoxm     
n.剧本,脚本;概要
参考例句:
  • But the birth scenario is not completely accurate.然而分娩脚本并非完全准确的。
  • This is a totally different scenario.这是完全不同的剧本。
7 coordinate oohzt     
adj.同等的,协调的;n.同等者;vt.协作,协调
参考例句:
  • You must coordinate what you said with what you did.你必须使你的言行一致。
  • Maybe we can coordinate the relation of them.或许我们可以调和他们之间的关系。
8 cholera rbXyf     
n.霍乱
参考例句:
  • The cholera outbreak has been contained.霍乱的发生已被控制住了。
  • Cholera spread like wildfire through the camps.霍乱在营地里迅速传播。
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