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SSS 2011-03-25

时间:2011-04-27 05:41来源:互联网 提供网友:geologyforget   字体: [ ]
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    (单词翻译:双击或拖选)

This is Scientific American's 60-Second Science. I'm Steve Mirsky. Got a minute?

It's been more than a decade since the human genome was published. And some critics have wondered where the promised medical applications are. Well, a review article in the current issue of The New England Journal of Medicine talks about how knowledge of a patient's genome is allowing doctors to pick the best drug for that patient, along with dosage and duration of treatment.

For example, last year the FDA added a warning to the prescribing info for the widely used anticlotting drug clopidogrel. Because patients with a particular genetic2 variant3 might not respond well to that drug. Another example is the antibiotic4 floxacillin. The drug helps treat most people's staph infections. But it's associated with liver problems in rare individuals carrying another specific gene1 set.

Unfortunately, it's still uncommon5 for docs to get genome info about patients, so that wealth of knowledge isn't often put into practice. Insurers don't want to cover widespread pharmacogenomic testing without lots of evidence that it's applicable. Which slows the accumulation of whatever drug-gene interaction evidence would be useful. Here's hoping that ever-cheaper genome analysis accelerates the use of genetic information.

Thanks for the minute. For Scientific American's 60-Second Science, I'm Steve Mirsky.


点击收听单词发音收听单词发音  

1 gene WgKxx     
n.遗传因子,基因
参考例句:
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
2 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
3 variant GfuzRt     
adj.不同的,变异的;n.变体,异体
参考例句:
  • We give professional suggestions according to variant tanning stages for each customer.我们针对每位顾客不同的日晒阶段,提供强度适合的晒黑建议。
  • In a variant of this approach,the tests are data- driven.这个方法的一个变种,是数据驱动的测试。
4 antibiotic KNJzd     
adj.抗菌的;n.抗生素
参考例句:
  • The doctor said that I should take some antibiotic.医生说我应该服些用抗生素。
  • Antibiotic can be used against infection.抗菌素可以用来防止感染。
5 uncommon AlPwO     
adj.罕见的,非凡的,不平常的
参考例句:
  • Such attitudes were not at all uncommon thirty years ago.这些看法在30年前很常见。
  • Phil has uncommon intelligence.菲尔智力超群。
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