访谈录 Interview 2007-02-24&26, 双胞胎聚会(在线收听

special thanks to foues

We are seeing double,. We got these fabulous sets of twins out here. And our guest Marilyn Hoyt from the Hall of Science in New York City. What kind of exhibit you guys have coming up.

Well, right now, we have an exhibit till May 6th on genome.

Which are, What is genome?

Well, our genes are essential the organizer of all the instructions of every cell. And that sounds harder than it is. The cool thing about the genome exhibition is it's both fun and learning. And the reason we have these twins is: A to note that Mayor Bloomberg has made today, en, February twin Ts.

Er, twin Ts, OK, I got it. So, this is an official Twin Day here in New York City, right?

And B these all people all have exactly the same genes. They have the same genome. Now all of us when we go to a museum are used to paying for one ticket for one person(Uh-huh), but during the genome exhibition, we'll be paying one ticket for one genome. So these pairs of twins all come in for one ticket.

I love it, great, and there's lots of great things, so we have some little ones here, lots of great parts of this exhibition for kids as well, right?

Yes, for all ages.

Alright, that's fantastic. Thank you so much for joining us Marilyn, it's a lot of fun, thanks twins. You guys look great. For more insight on twins, which is becoming so popular, now we go back inside to Harry, hey, Harry.

Hi, thanks very much, Hannah. Believe it or not, identical twins are only a little more alike than the rest of us. That's because all human beings are 99.9% the same, that is genetically. Thomas Turi, director of genetic technologies for Pfizer is here to explain a little bit more. Good morning.

Good morning.

So how much the same are you and I?

You and I and everyone else are 99.9% identical.

Right, and the twins that we are looking at out, especially the guys with the funny hats on , how identical, how how much the same are they?

Well, depends on whether they are maternal twins or fraternal twins. Maternal twins are 100% identical.

These guys?

These guys, 100% identical. Er, that's because after the egg has been fertilized, it splits and divides, so they actually share the same genetic material for, for very early stages.

As a researcher, what kind of information does that tell you, what is the, well, how is that helpful to you?

So twin's studies are actually very helpful in terms of trying to help identify and localize genes that cause disease. (Right) Many diseases, yet not all diseases have a genetic component. (Right)And some diseases have a genetic component as well as an environmental component.

Sure, sure, sure, so when we were looking at these pictures of twins, we've heard so much a couple of years about, about mapping the genome and everything like, like that. Do we know that much more now than, say, we did five years ago?

Well, we now we have the entire genome for human as well as many mammal species. And one of the results of this is many identification of many diseases causing genes.

Right, that's good news and bad news and which is just saying, there are two times we'll think about a lot especially when we are getting ready to plan a family and when we’re for turning 55 years or older so. Because of genetic propensities, now that's, is that a blessing and or a curse or, you don't understand where I am going with this (Alright) because we can certainly make certain choices if I'm 55 years old. I can do things to help myself live better and live longer. But should/ we be in a position of making choices about the lives of, of unborn children?

Well, discoveries related to the human genome have tremendous potential to impact our lives and our healthcare. Unless we are prepared and educated on topics like genome, people may find themselves unprepared to make those types of decisions.

Yeah, how did these impact of, you work for a big pharmaceutical company. Er, is part of what you do looking from the connection between a genetic default, so to speak, and finding out ways to prolong life for instance, or stop, stop a genetic default from setting the disease in the first place? Is that possible?

Well, discoveries related to the human genome again have tremendous potential to impact our lives and Pfizer is committed to trying to a capitalized er, new technologies that will help us discover disease causing genes.

Yeah, did you read the stuff the other day about this notion they think they may have sort of found that or, autism is, is, genetically, genetically based?

Well again, most diseases have a genetic component, and people, the scientists all over the world that are trying to uncover these disease caused in genes, for diseases, or conditions like autism, cancer, obesity.

Yeah.
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