2007年VOA标准英语-New Pill Developed to Curb Alcoholism

By Melinda Smith
Washington
12 July 2007
 

Alcoholism is a growing problem worldwide.  The World Health Organization reports that alcohol causes almost two million deaths every year and results in physical disability or shortened life span for at least 58 million others.  Now a drug -- already used to help smokers¹ cut back -- is showing promise as a way to reduce alcohol consumption.  VOA's Melinda Smith has the story.

Varenicline

The pill's name is varenicline and it is already on the market in the U.S. and Canada as a remedy for smoking under the brand name Chantix.  Its European name is Champix.

No research on the drug as a treatment for alcoholism has been done yet on humans.  But one study on rats shows varenicline cuts desire for alcohol by 50 percent.  The rats do not exhibit excessive drinking even after they are no longer given the drug.

That reduced desire for alcohol could be a key element in any future testing on humans.  Often alcoholics² tend to go back to drinking after they quit taking any of the current drugs on the market. 

Dr. Salena Bartlett

The study's author is Dr. Selena Bartlett of the University of California San Francisco. She says medication options are few for treating alcoholism. "There are very few effective medicines to treat alcoholism.  Our hope is that this drug will provide a new and improved method for treating alcoholism."

Varenicline has been available for about a year as a treatment to curb³ nicotine⁴ addiction⁵.  Dr. Bartlett thinks it will help drinkers too. ”There is a huge link in smoking and drinking."

Eighty-five percent of alcoholics are also believed to smoke, and researchers are hoping patients would then be able to take one drug for both conditions.

The World Health Organization says most of the increase in global alcohol consumption is happening in developing countries.  The WHO says alcoholism is occurring in places where drinking has not been a traditional part of the culture and there are few treatment programs available.

Dr. Bartlett believes successful treatment with varenicline may be possible because it targets the center of the brain, which releases dopamine -- the 'feel good' neurotransmitter that is temporarily triggered by drugs, cigarettes or alcohol.  Varenicline shuts down the release of dopamine, which then shuts off the desire.

While the drug shows promise, researchers caution that its release to the public is still a long way off.  Even then, they say, curing alcoholism will take more than just swallowing a pill.

1 smokers   

吸烟者( smoker的名词复数 )

参考例句：

• Many smokers who are chemically addicted to nicotine cannot cut down easily. 许多有尼古丁瘾的抽烟人不容易把烟戒掉。
• Chain smokers don't care about the dangers of smoking. 烟鬼似乎不在乎吸烟带来的种种危害。

2 Alcoholics   

n.嗜酒者，酒鬼( alcoholic的名词复数 )

参考例句：

• Many alcoholics go on drinking sprees that continue for days at a time. 许多酒鬼一次要狂饮好几天。 来自《现代汉英综合大词典》
• Do you have a copy of the Alcoholics Anonymous book? 你手上有戒酒匿名会的书吗？ 来自互联网

3 curb   

n.场外证券市场，场外交易；vt.制止，抑制

参考例句：

• I could not curb my anger.我按捺不住我的愤怒。
• You must curb your daughter when you are in church.你在教堂时必须管住你的女儿。

4 nicotine   

n.(化)尼古丁，烟碱

参考例句：

• Many smokers who are chemically addicted to nicotine cannot cut down easily.许多有尼古丁瘾的抽烟人不容易把烟戒掉。
• Many smokers who are chemically addicted to nicotine cannot cut down easily.许多有尼古丁瘾的抽烟人不容易把烟戒掉。

5 addiction   

n.上瘾入迷，嗜好

参考例句：

• He stole money from his parents to feed his addiction.他从父母那儿偷钱以满足自己的嗜好。
• Areas of drug dealing are hellholes of addiction,poverty and murder.贩卖毒品的地区往往是吸毒上瘾、贫困和发生谋杀的地方。